Primary care providers are generally not well trained in handling complicated mood problems. Some have gotten really good at […]

The discussion below focuses on evolution as a principle. Perhaps more important, or at least easier to swallow, […]

Here are all the pages on this site, by Topic.  Click across the three tabs below. You could […]

What to Look For and Questions to Ask (This is a whole chapter on the subject which didn’t […]

Randomized Trials of Antidepressants in Bipolar Disorder If you arrived here from somewhere other than the Antidepressant Controversies […]

Here are some findings from a literature search on this topic 1. In one study, doctors gave eight […]

Is there a “testosterone deficiency syndrome”? Update 10/2020:  A randomized controlled trial was just published in the American […]

Here’s a short version of a long, important story:  genes can be modified, during life, and those modifications […]

How? What’s the connection? Recent reviews emphasized that there seems to be a “two-way street” between metabolic syndrome […]

In contrast to mania, depression is now quite well understood at a molecular and cellular level. Even some […]

This is a hard chapter. If there are any in this series of five chapters you might wish […]

Whereas 10 years ago it was hoped that a single gene for bipolar disorder might be found, it […]

BCL-2 stands for B-cell lymphoma/leukemia-2, one of a large family of proteins that regulate cell death and growth. […]

(if you didn’t get here from the middle of Chapter 9, go back to the beginning of that […]