When depression gets worse on an antidepressant, it doesn’t necessarily mean the patient has bipolar disorder or that […]
Category Archive: Controversies
How do methylphenidate (Ritalin), modafinil (Provigil), and caffeine affect memory and attention? A new study compares them in healthy men.
There are at least 9 alternatives with at least as much evidence as antidepressants for effectiveness in bipolar […]
The bottom line: Switching happens, but how often seems to vary widely, depending on the study you look […]
Should you continue antidepressants or stop them in bipolar disorder? Here’s the research.
Can antidepressants stop working in bipolar disorder? Can they cause tolerance?Here’s the evidence.
Do antidepressants destabilize mood in bipolar disorder? It looks like they can, and here’s the evidence.
Antidepressants can cause mania, but how often they do depends on the study.
Antidepressants usually don’t work in bipolar disorder, but a few people respond well to them. It’s just hard to know who they are.
More than a few patients have heard me admit: “well, your drug is better than my drugs.” We’ve […]
Summary When a patient with bipolar disorder is taking an antidepressant, and the decision is made to stop […]
Revised 11/2014 The United States Food and Drug Administration (FDA) raised a huge controversy when it required a […]
Altshuler and Ghaemi Psychiatric Times no longer offers the original, actual essays. For historical purposes these seemed worth saving. […]
Is there Some Evolutionary Advantage to Bipolar? Evolution did not select out bipolar disorder because the genes which […]
(Here’s a summary on the use of this agent in bipolar disorder). Update 2014: there was a lot […]
Summary Lithium orotate might be a good idea, especially for some people. It may have some risks too. […]
Two weeks before the DSM- 5 came out, the head of the National Institute of Mental Health (NIMH) […]
A reader forwarded the graph and the table below, inviting their inclusion. Although these are the work of […]