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Category Archive: Brain Tours

Chapter 12: Putting it all Together

Genes, Stress, Depression and Atrophy Knowing, at a biological level, that a big part of the problem is […]

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Chapter 11: Can the Shrinkage Be Reversed?

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Key areas of the brain shrink during depression, post-traumatic stress (PTDS), and bipolar disorder, but the shrinkage can be reversed. Here’s how the brain repairs the emotion and memory centers (the amygdala and hippocampus).

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Chapter 10: All the Players on One Stage

You’ve seen the stress factors (cortisol, CRF), and the trophic factors (BDNF and friends). This chapter slowly assembles […]

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Chapter 9: Some Good News: Anti-shrink Molecules!

Although stress and depression can make brain cells shrink, there’s good news. The brain has built-in neuroprotective chemicals that repair the damage.

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Chapter 8: What is Causing Brain Atrophy in Depression?

Stress causes depression through hormones like cortisol. When these “stress hormones” rise too high for too long, it affects key areas in the brain involved in depression.

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Chapter 7: Why do Some Parts of the Brain Atrophy during Major Depression?

In Chapter 6 we saw that severe mood symptoms are associated with hippocampal shrinkage (atrophy). In this chapter, […]

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Chapter 6: What Happens inside People’s Brains when they’re Depressed?

Stress and depression can cause cells to shrink in the brain’s memory and emotion center (the hippocaumps and amygdala). Here’s how.

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Chapter 5: Hey, Where do I Get my Genes Tested?

Testing for the short serotonin transporter allele If you’ve had a rough childhood and long struggle with depression, […]

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Chapter 4: Short Genes in Anxiety and Depression

or Why Are There Shorts and Longs? Warning: This is one of the more difficult chapters. Don’t skip […]

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Chapter 2: Short genes are involved other mental health problems too

The short arm of the serotonin transporter gene (S/S) doesn’t just increase the risk of depression. It’s involved in anxiety and alcohol abuse as well, and it may predict response to antidepressants.

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Chapter 1: Why are some people so affected by stress?

The short arm of the serotonin transporter gene (S/S) increases the risk of depression by changing the way the brain responds to stress. Here’s how.

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