Online Guides

The Mood Spectrum

1 in 3 people with depression fall in the middle of the mood spectrum (aka bipolar spectrum). Learn what that means and how to treat it.

Antidepressants in Bipolar

Learn whether they work, when they make things worse, and how to come off them

Genes, Stress, and the Brain

How genes interact with stress to shape the brain

The Bipolar Brain

Mechanisms and causes of bipolar and depression

Recent Articles

• Duloxetine (Cymbalta) Patient Guide: Benefits, Dosing, and Side Effects Explained
  by Sebastian Malleza, M.D., M.Sc.
  This guide is adapted from the clinician guide authored by Sebastián Malleza, M.D., M.Sc. at the Psychopharmacology Institute. For the complete clinical resource, visit: Duloxetine Guide: Pharmacology, Indications, Dosing Guidelines and Adverse Effects What is Duloxetine? Duloxetine (brand name Cymbalta)… Read more: Duloxetine (Cymbalta) Patient Guide: Benefits, Dosing, and Side Effects Explained
• Desvenlafaxine (Pristiq) Patient Guide: Benefits, Dosing, and Side Effects Explained
  by Sebastian Malleza, M.D., M.Sc.
  This guide is adapted from the clinician guide authored by Sebastián Malleza, M.D., M.Sc. at the Psychopharmacology Institute. For the complete clinical resource, visit: Desvenlafaxine Guide: Pharmacology, Indications, Dosing Guidelines and Adverse Effects What is Desvenlafaxine? Desvenlafaxine (brand name Pristiq)… Read more: Desvenlafaxine (Pristiq) Patient Guide: Benefits, Dosing, and Side Effects Explained
• Vortioxetine (Trintellix) Patient Guide: Benefits, Dosing, and Side Effects Explained
  by Sebastian Malleza, M.D., M.Sc.
  This guide is adapted from the clinician guide authored by Sebastián Malleza, M.D., M.Sc. at the Psychopharmacology Institute. For the complete clinical resource, visit: Vortioxetine Guide: Pharmacology, Indications, Dosing Guidelines and Adverse Effects What is Vortioxetine? Vortioxetine (brand… Read more: Vortioxetine (Trintellix) Patient Guide: Benefits, Dosing, and Side Effects Explained
• Levomilnacipran (Fetzima) Patient Guide: Benefits, Dosing, and Side Effects Explained
  by Flavio Guzman, M.D.
  This guide is adapted from the clinician guide authored by Sebastián Malleza, M.D., M.Sc. at the Psychopharmacology Institute. For the complete clinical resource, visit: Levomilnacipran Guide: Pharmacology, Indications, Dosing Guidelines and Adverse Effects What is Levomilnacipran? Levomilnacipran (brand… Read more: Levomilnacipran (Fetzima) Patient Guide: Benefits, Dosing, and Side Effects Explained
• Lithium Orotate
  by Jim Phelps, M.D.
  Summary Lithium orotate might be a good idea, especially for some people. It may have some risks too. We don’t really know. (Those who claim low risk don’t know either). You may be willing to pay for it,… Read more: Lithium Orotate
• Manic Episodes: How to Prevent Them and How to Help
  by Flavio Guzman, M.D.
  This guide provides useful strategies to prevent manic episodes. It suggests maintaining a daily routine, avoiding triggers, following prescribed medication plans, and practicing self-care. The guide also recommends creating a safety plan to prepare for potential manic episodes.… Read more: Manic Episodes: How to Prevent Them and How to Help
• A Guide to Mania: Recognizing A Manic Episode
  by Flavio Guzman, M.D.
  The article explores mania, a syndrome marked by extreme energy and varying emotions, commonly seen in bipolar I disorder. It simplifies the DSM-5 diagnostic criteria and offers fictional case studies of ‘Jack’ and ‘Jessica’ to demonstrate the disruptive… Read more: A Guide to Mania: Recognizing A Manic Episode

Paper Books

Depression and Bipolar Workbook

30 lifestyle changes you can make that treat depression and stabilize bipolar.

A Spectrum Approach to Mood Disorders

A practical textbook for physicians, nurses, therapists, and those who want to understand the science behind the spectrum.

Bipolar, Not So Much

How the mood spectrum looks in real life, with detailed chapters on natural therapies, medications, and tips for friends and family.

Also available on audio.

Favorites

1. Diagnosis in the Mood Spectrum
2. Depression is not a Moral Weakness
3. Mixed States, Depression & Anxiety
4. Treatment Basics: The Middle of the Mood Spectrum
5. Antidepressants that aren’t “Antidepressants”
6. How to Choose a Mood Stabilizer
7. Dark Therapy for Sleep and Bipolar